Jim,
I like the design of your bullet. I personally would not go with a nose radius smaller for a .40-65 if your planning to use it for past 600 yards. That nose you have will do a fine job. I think if you put some of those with 1/16 alloy and not softer then 1/18 with a smidge of poison antimony

in the snow and look at them when you find them I don't think you will be disappointed.
I saw something last winter that was a real eye opener for me. I tested the 14 twist .40-65 with different alloys as well the .45-90 with the same alloy and I always figured the .45's would get more nose setback then the lighter .40's but not so. The .40-65 had the nose setback more with 60 gr of 1.5 Swiss then the .45-90 that had 83 gr of 1.5 Swiss shot at the same time in the same pile.
I have elliptical .40's and prolate 40's and they don't hold up as well as the original bullet design of the original like the one in the .44-77 below. That design will hold up as far as your sights will allow you to shoot the rifle.
Kurt